Masters of the Hospital
John Campden (fl. 1399)
John Lockman (until 1807)
The Venerable Canon Michael Harley, subsequently Archdeacon of Winchester from 2009 to 2015
The Reverend Reg Sweet (current as of January 2017)
Francis North, Earl of Guilford, son of a previous Bishop of Winchester, was Rector of St. Cross from 1829, and the long lasting enquiries into the large revenue that he received as such formed the inspiration for the novel The Warden by Anthony Trollope.